Sentieon 202112.02版本于2022年4月2日正式发布,在此版本中添加添加了众多功能和性能优化:

新功能

- 升级了DNAscope的机器学习模型模块;
- 进一步提升了Sentieon BWA在某些ARM架构CPU平台上的计算效率;
- 添加了对多个测序平台的许可框架支持;

Bug修复

- Solved issue in GVCFtyper that would produce no-calls in certain ploidies when input is a multi-sample merged gVCF from third party tool.
- Solved issue in DNAscope that could produce no call at zero coverage site when using --given.
- Solved issue that triggered CRAM buffer overflow when minimap2 output zero-length secondary reads
- Solved issue in minimap2 that would cause the job to hang under rare circumstances.